I tried ep2 of Last One Laughing - I am just left scratching my head.
The problem isn't how good or bad the comedians are (it obviously helps if you like them, but you really have to like them), it's that the concept is suicidal - even when they come up with some good lines, they are immediately undermined by the flat reaction, it constantly feels like comedians dying on stage in front of a hostile or indifferent audience.
And the only people laughing are "the friends table in the left corner" in the control room, with Roisin Conaty repeating "oh this is so funny" as if she is trying to convince herself and others.