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Coronavirus


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https://www.theguardian.com/world/2021/oct/01/covid-antiviral-pill-halves-hospitalisations-and-deaths-maker-says

 

An antiviral pill was found to reduce hospitalisations and deaths by half in patients newly diagnosed with Covid-19, according to results announced on Friday.

If approved, the drug made by the US firm Merck and Ridgeback Biotherapeutics would be the first simple oral medication shown to be effective against Covid-19, which would mark a crucial advance in the fight against the pandemic. Other drugs, such as remdesivir, have been shown to be effective if given early, but all currently approved treatments need to be given as injections or IV infusions.


Merck said it would apply for emergency use authorisation for the drug in the US within the next two weeks and seek approval in several other countries.

The trial tracked 775 adults with mild to moderate Covid, who were considered higher risk for severe disease owing to health problems such as obesity, diabetes or heart disease. Half were given a five-day course of the pill, called molnupiravir. In the placebo group, 53 patients (14%) were hospitalised compared with only 28 (7%) of those who received the drug. There were no deaths in the drug group after that time period compared with eight deaths in the placebo group, according to Merck.

 

The data from the study was made public in a press release and has not yet been peer-reviewed. However, an independent group of medical experts monitoring the trial recommended stopping it early because the interim results were so encouraging.

“It exceeded what I thought the drug might be able to do in this clinical trial,” said Dean Li, the vice-president of Merck research. “When you see a 50% reduction in hospitalisation or death that’s a substantial clinical impact.”


Only limited information on side-effects was made public in the press release, but the companies said rates were similar between the placebo group and the treated group. An adverse event, or bad outcome, occurred in 35% of those who received molnupiravir and 40% of those who received placebo. Only 1.3% of participants who received the drug discontinued treatment because of an adverse event, compared with 3.4% who discontinued the placebo.

A convenient pill that patients could take when Covid symptoms first appear has long been viewed as a crucial goal in controlling future waves of infection and reducing the ongoing impact of the pandemic.

 

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1 hour ago, Jairzinho said:

https://www.theguardian.com/world/2021/oct/01/covid-antiviral-pill-halves-hospitalisations-and-deaths-maker-says

 

An antiviral pill was found to reduce hospitalisations and deaths by half in patients newly diagnosed with Covid-19, according to results announced on Friday.

If approved, the drug made by the US firm Merck and Ridgeback Biotherapeutics would be the first simple oral medication shown to be effective against Covid-19, which would mark a crucial advance in the fight against the pandemic. Other drugs, such as remdesivir, have been shown to be effective if given early, but all currently approved treatments need to be given as injections or IV infusions.


Merck said it would apply for emergency use authorisation for the drug in the US within the next two weeks and seek approval in several other countries.

The trial tracked 775 adults with mild to moderate Covid, who were considered higher risk for severe disease owing to health problems such as obesity, diabetes or heart disease. Half were given a five-day course of the pill, called molnupiravir. In the placebo group, 53 patients (14%) were hospitalised compared with only 28 (7%) of those who received the drug. There were no deaths in the drug group after that time period compared with eight deaths in the placebo group, according to Merck.

 

The data from the study was made public in a press release and has not yet been peer-reviewed. However, an independent group of medical experts monitoring the trial recommended stopping it early because the interim results were so encouraging.

“It exceeded what I thought the drug might be able to do in this clinical trial,” said Dean Li, the vice-president of Merck research. “When you see a 50% reduction in hospitalisation or death that’s a substantial clinical impact.”


Only limited information on side-effects was made public in the press release, but the companies said rates were similar between the placebo group and the treated group. An adverse event, or bad outcome, occurred in 35% of those who received molnupiravir and 40% of those who received placebo. Only 1.3% of participants who received the drug discontinued treatment because of an adverse event, compared with 3.4% who discontinued the placebo.

A convenient pill that patients could take when Covid symptoms first appear has long been viewed as a crucial goal in controlling future waves of infection and reducing the ongoing impact of the pandemic.

 

So that's why Merck said Ivermectin was no good.

 

Texas Governor's Tinfoil Hat Would Actually Help The Government Read His  Mind

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4 hours ago, Bruce Spanner said:

Rumours abound that travel lists will all be scrapped internationally and vaccine reports and locally approved pre testing will be the only requirement for all international travel soon as the aviation/travel industry is on the verge of failure and they see this as the only real hope of saving it/boosting economies globally.

 

Fingers crossed.

I travelled to Spain last week via Gatwick. I was quite shocked to see one terminal still closed. There must be so many jobs, from the transport, retail and catering, supply chain that are not directly related to airlines that must be fucked right now - with government support now finishing. They've got to do something. They either determine we're back to normal, which needs to mean back to normal - or they need to continue supporting these industries that are compromised by differing covid bans. 

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4 minutes ago, Barrington Womble said:

I travelled to Spain last week via Gatwick. I was quite shocked to see one terminal still closed. There must be so many jobs, from the transport, retail and catering, supply chain that are not directly related to airlines that must be fucked right now - with government support now finishing. They've got to do something. They either determine we're back to normal, which needs to mean back to normal - or they need to continue supporting these industries that are compromised by differing covid bans. 


It’s like in the very first weeks of this when they allowed the pubs to stay open, but told customers to stay away.

 

Just ill thought out, fag packet planning with it all. 
 

I don’t know what the answer is as in the UK things are in a weird hinterland where everyone is just pretending it isn’t happening anymore as the cases and deaths creep up again.

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4 minutes ago, TheHowieLama said:

Energy and food. That is what is going to come to. In the next 25 years the places that can deal with that effectively - which may mean drastically increased nationalisation/localisation of those chains will prosper. 


And why Billionaires and funds are buying up arable land whenever and wherever they can.

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8 minutes ago, Bruce Spanner said:


It’s like in the very first weeks of this when they allowed the pubs to stay open, but told customers to stay away.

 

Just ill thought out, fag packet planning with it all. 
 

I don’t know what the answer is as in the UK things are in a weird hinterland where everyone is just pretending it isn’t happening anymore as the cases and deaths creep up again.

Yeah I don't know the answer either. But we spent lockdown with the aim that the vaccine is the solve all silver bullet. There's not another one arriving, so we either have to accept what we've got now is long term and needs long term support or we have to just find new ways to try and return to normal and quickly. 

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1 minute ago, MegadriveMan said:

Have people always been this odd?

 

How can you claim to be normal people whilst standing outside of a TV Doctors house having a go at him with a megaphone?

 

I don’t think they’ve had 

a) a big enough cause

b) the ability to meet other cranks via the internet 

 

Perfect storm.  It allows idiots the opportunity to feel superior.  

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30 minutes ago, MegadriveMan said:

Have people always been this odd?

 

How can you claim to be normal people whilst standing outside of a TV Doctors house having a go at him with a megaphone?

 

They've done their research.... wankers 

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16 hours ago, Rico1304 said:

I don’t think they’ve had 

a) a big enough cause

b) the ability to meet other cranks via the internet 

 

Perfect storm.  It allows idiots the opportunity to feel superior.  

The internet has been the worst part for this. It gives them mates who they've never met to feel validated and ideas to continue the crazy. 

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I've just had the booster but my Grandson (9) has tested positive for his 2nd bout.

Headaches and temperature so far, but he's alright in himself.

It started on Thursday when Mrs HL picked him up from school and took him home along with 2 of the other Grandkids, which is unfortunate, so fingers crossed for all of them.

 

 

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20 minutes ago, Harry's Lad said:

I've just had the booster but my Grandson (9) has tested positive for his 2nd bout.

Headaches and temperature so far, but he's alright in himself.

It started on Thursday when Mrs HL picked him up from school and took him home along with 2 of the other Grandkids, which is unfortunate, so fingers crossed for all of them.

 

 

Best wishes to your Grandson, let’s hope the others avoid the blinking thing. 

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1 hour ago, Rico1304 said:

 

First line :

 

Quote

Anti-vaxxers are selling horse drugs in London claiming they are an alternative to the vaccine.

 

I don't think the images there are showing horse drugs. If so the journo there has either got that wrong or is deliberately lying which wouldn't be the first time when it comes to reporting on ivermectin.

 

Here's the source article : https://www.mirror.co.uk/news/uk-news/conman-selling-horse-drugs-covid-25123790

 

If you look at one of the images there you might be able to make out "MSD" and "32", which is the same as here : https://www.drugs.com/imprints/32-msd-8205.html

 

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1 hour ago, Rico1304 said:

 

Also :

 

The admin falsely claimed: “Treatments have been proven safe for children to the elderly including pregnant women. In other parts of the world [they] are sold over the counter."

 

Even Merck advise against using it during pregnancy so that's seriously fucked if they actually said that.

 

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On 02/10/2021 at 17:07, Rico1304 said:

Wouldn’t it be great if Hilary just calmly walked up to this cunt and and knocked him out? 
 

 

Zzzz.   Useless cunts.  Doc Hillary could stand in front them and take a lazy piss and they wouldn't do anything.  Fuck off fat-arse, you've got nothing, just an online stunt.  Zzzz. 

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